4F4D
F337R variant of human ferrochelatase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ferrochelatase, mitochondrial | polymer | 359 | 41188.4 | 2 | UniProt (P22830) Pfam (PF00762) | Homo sapiens (human) | Heme synthase, Protoheme ferro-lyase |
| 2 | C, I (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 3 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | E, J (A, B) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 5 | F, G, H, K, L... (A, B) | CHOLIC ACID | non-polymer | 408.6 | 6 | Chemie (CHD) | |||
| 6 | N, O (A, B) | water | water | 18.0 | 604 | Chemie (HOH) |
Sequence modifications
A, B: 65 - 423 (UniProt: P22830)
| PDB | External Database | Details |
|---|---|---|
| Arg 337 | Phe 337 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82376.8 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2966.1 | |
| All* | Total formula weight | 85342.9 |
