4F3K
Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with homocysteine-DADMe-Immucillin-A
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | polymer | 248 | 26324.1 | 2 | UniProt (E8NLP5) In PDB | Salmonella enterica subsp. enterica serovar Choleraesuis | MTA/SAH nucleosidase, MTAN, 5'-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase |
2 | A, B | {(3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-hydroxypyrrolidin-3-yl}-L-methionine | non-polymer | 380.5 | 2 | Chemie (HCE) | |||
3 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
4 | water | water | 18.0 | 247 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 232 (UniProt: E8NLP5)
PDB | External Database | Details |
---|---|---|
Met -15 | - | initiating methionine |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
Gly -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 52648.1 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 885.1 | |
All* | Total formula weight | 53533.2 |