4EY5
Crystal Structure of Recombinant Human Acetylcholinesterase in Complex with (-)-huperzine A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Acetylcholinesterase | polymer | 542 | 59447.1 | 2 | UniProt (P22303) Pfam (PF00135) | Homo sapiens (human) | AChE |
| 2 | C, D (C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
| 3 | E, J (A, B) | Huperzine A | non-polymer | 242.3 | 2 | Chemie (HUP) | |||
| 4 | F, K (A, B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 5 | G, H, L (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 6 | I (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | M, N (B) | NITRATE ION | non-polymer | 62.0 | 2 | Chemie (NO3) | |||
| 8 | O, P (A, B) | water | water | 18.0 | 371 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 118894.2 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1141.1 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1172.3 | |
| All* | Total formula weight | 121207.6 |
