4EWH
Co-crystal structure of ACK1 with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Activated CDC42 kinase 1 | polymer | 275 | 31503.3 | 2 | UniProt (Q07912) Pfam (PF07714) | Homo sapiens (human) | ACK-1, Tyrosine kinase non-receptor protein 2 |
| 2 | C, D (B, A) | 6-{4-[2-(dimethylamino)ethoxy]phenyl}-N-(1,3-dithiolan-2-ylmethyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine | non-polymer | 491.7 | 2 | Chemie (T77) | |||
| 3 | E, F (B, A) | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63006.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 983.3 | |
| All* | Total formula weight | 63989.9 |
