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4EWH

Co-crystal structure of ACK1 with inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1B, AActivated CDC42 kinase 1polymer27531503.32UniProt (Q07912)
Pfam (PF07714)
In PDB
Homo sapiens (human)ACK-1, Tyrosine kinase non-receptor protein 2
2B, A6-{4-[2-(dimethylamino)ethoxy]phenyl}-N-(1,3-dithiolan-2-ylmethyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-aminenon-polymer491.72Chemie (T77)
3waterwater18.023Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight63006.6
Non-Polymers*Number of molecules2
Total formula weight983.3
All*Total formula weight63989.9
*Water molecules are not included.

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PDB entries from 2024-03-27

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