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4EW4

mouse MBD4 glycosylase domain in complex with DNA containing a ribose sugar

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Methyl-CpG-binding domain protein 4polymer14617564.21UniProt (Q9Z2D7)Mus musculus (Mouse)Methyl-CpG-binding protein MBD4,Mismatch-specific DNA N-glycosylase
2B
(B)
DNA (5'-D(*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3')polymer113374.21synthetic construct
3C
(C)
DNA (5'-D(*CP*CP*AP*TP*GP*(3DR)P*GP*CP*TP*GP*A)-3')polymer113225.11synthetic construct
4D
(A)
NICKEL (II) IONnon-polymer58.71Chemie (NI)
5E
(A)
UNKNOWN ATOM OR IONnon-polymer103.11Chemie (UNX)
6F, G, H
(A, B, C)
waterwater18.018Chemie (HOH)
Sequence modifications
A: 411 - 554 (UniProt: Q9Z2D7)
PDBExternal DatabaseDetails
His 409-expression tag
Met 410-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight24163.5
Non-Polymers*Number of molecules2
Total formula weight161.8
All*Total formula weight24325.3
*Water molecules are not included.

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PDB entries from 2024-11-06

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