4EUZ
Crystal structure of serratia fonticola carbapenemase SFC-1 S70A-Meropenem complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Carbapenem-hydrolizing beta-lactamase SFC-1 | polymer | 283 | 30809.8 | 1 | UniProt (Q6JP75) | Serratia fonticola | |
| 2 | B (A) | (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid | non-polymer | 383.5 | 1 | Chemie (MEM) PubChem (18640433) PubChem (18657686) PubChem (29920942) PubChem (42646972) PubChem (60707) PubChem (44290528) PubChem (44421088) PubChem (51405094) PubChem (51435910) PubChem (51436195) PubChem (57404065) PubChem (57921071) PubChem (58648993) PubChem (44717105) PubChem (59958246) PubChem (441130) PubChem (67474993) PubChem (67750078) PubChem (68272636) PubChem (70943366) PubChem (51436193) PubChem (73707470) PubChem (86633688) PubChem (3874387) PubChem (91746186) PubChem (92276926) PubChem (92276932) PubChem (94004154) PubChem (6604449) PubChem (9800191) PubChem (121274551) PubChem (123134854) PubChem (10317807) PubChem (13504356) PubChem (124762017) PubChem (124762018) PubChem (13504355) PubChem (13504357) PubChem (126757688) PubChem (134352762) PubChem (134692530) PubChem (135211940) PubChem (137705018) PubChem (167255290) PubChem (168310808) PubChem (169995788) PubChem (172012140) | |||
| 3 | C, D, E, F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | G, H, I, J, K... (A) | SODIUM ION | non-polymer | 23.0 | 7 | Chemie (NA) PubChem (923) | |||
| 5 | N (A) | water | water | 18.0 | 494 | Chemie (HOH) |
Sequence modifications
A: 22 - 305 (UniProt: Q6JP75)
| PDB | External Database | Details |
|---|---|---|
| Ala 70 | Ser 74 | engineered mutation |
| Ala 255 | Gly 259 | SEE REMARK 999 |
| Arg 270 | Lys 274 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30809.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 792.7 | |
| All* | Total formula weight | 31602.4 |
