4EUZ
Crystal structure of serratia fonticola carbapenemase SFC-1 S70A-Meropenem complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Carbapenem-hydrolizing beta-lactamase SFC-1 | polymer | 283 | 30809.8 | 1 | UniProt (Q6JP75) Pfam (PF00144) Pfam (PF13354) | Serratia fonticola | |
| 2 | B (A) | (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid | non-polymer | 383.5 | 1 | Chemie (MEM) | |||
| 3 | C, D, E, F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | G, H, I, J, K... (A) | SODIUM ION | non-polymer | 23.0 | 7 | Chemie (NA) | |||
| 5 | N (A) | water | water | 18.0 | 494 | Chemie (HOH) |
Sequence modifications
A: 22 - 305 (UniProt: Q6JP75)
| PDB | External Database | Details |
|---|---|---|
| Ala 70 | Ser 74 | engineered mutation |
| Ala 255 | Gly 259 | SEE REMARK 999 |
| Arg 270 | Lys 274 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30809.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 792.7 | |
| All* | Total formula weight | 31602.4 |
