4ESW

Crystal structure of C. albicans Thi5 H66G mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Pyrimidine biosynthesis enzyme THI13	polymer	342	38625.2	2	UniProt (C4YMW2) Pfam (PF09084)	Candida albicans (yeast)
2	C, D (A, B)	CITRIC ACID	non-polymer		192.1	2	Chemie (CIT)
3	E, F (A, B)	water	water		18.0	818	Chemie (HOH)

Sequence modifications

A, B: 1 - 339 (UniProt: C4YMW2)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Gly 66	His 66	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	77250.3
Non-Polymers*	Number of molecules	2
	Total formula weight	384.2
All*	Total formula weight	77634.6

*Water molecules are not included.