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4ESR

Molecular and Structural Characterization of the SH3 Domain of AHI-1 in Regulation of Cellular Resistance of BCR-ABL+ Chronic Myeloid Leukemia Cells to Tyrosine Kinase Inhibitors

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Jouberinpolymer697954.72UniProt (Q8N157)
Pfam (PF00018)
Homo sapiens (human)Abelson helper integration site 1 protein homolog, AHI-1
2C, D, E
(B)
DI(HYDROXYETHYL)ETHERnon-polymer106.13Chemie (PEG)
3F, G
(A, B)
waterwater18.0166Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight15909.3
Non-Polymers*Number of molecules3
Total formula weight318.4
All*Total formula weight16227.7
*Water molecules are not included.

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PDB entries from 2024-11-13

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