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4ESG

X-ray structure of WDR5-MLL1 Win motif peptide binary complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
WD repeat-containing protein 5polymer31234303.92UniProt (P61964)
Pfam (PF00400)
Homo sapiens (human)BMP2-induced 3-kb gene protein
2C, D
(C, D)
Histone-lysine N-methyltransferase MLLpolymer171884.12UniProt (Q03164)Homo sapiensALL-1, CXXC-type zinc finger protein 7, Lysine N-methyltransferase 2A, KMT2A, Trithorax-like protein, Zinc finger protein HRX, MLL cleavage product N320, N-terminal cleavage product of 320 kDa, p320, MLL cleavage product C180, C-terminal cleavage product of 180 kDa, p180
3E, F, G, H
(A, B, C, D)
waterwater18.0627Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight72376.0
All*Total formula weight72376.0
*Water molecules are not included.

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PDB entries from 2025-12-17

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