4EP9

CRYSTAL STRUCTURE OF RAT CARNITINE PALMITOYLTRANSFERASE 2 IN COMPLEX WITH CoA-site inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Carnitine O-palmitoyltransferase 2, mitochondrial	polymer	653	73566.1	1	UniProt (P18886) Pfam (PF00755)	Rattus norvegicus (brown rat rat rats)	Carnitine palmitoyltransferase II, CPT II
2	B (A)	4-[({1-[(5-chloro-2-methoxyphenyl)sulfonyl]-4-methyl-2,3-dihydro-1H-indol-6-yl}carbonyl)amino]benzoic acid	non-polymer		501.0	1	Chemie (0RD)
3	C (A)	PALMITIC ACID	non-polymer		256.4	1	Chemie (PLM)
4	D (A)	water	water		18.0	407	Chemie (HOH)

Sequence modifications

A: 27 - 658 (UniProt: P18886)

PDB	External Database	Details
Met 6	-	expression tag
Gly 7	-	expression tag
Ser 8	-	expression tag
Ser 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
Ser 16	-	expression tag
Ser 17	-	expression tag
Gly 18	-	expression tag
Leu 19	-	expression tag
Val 20	-	expression tag
Pro 21	-	expression tag
Arg 22	-	expression tag
Gly 23	-	expression tag
Ser 24	-	expression tag
His 25	-	expression tag
Met 26	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	73566.1
Non-Polymers*	Number of molecules	2
	Total formula weight	757.4
All*	Total formula weight	74323.5

*Water molecules are not included.