4EOZ
Crystal structure of the SPOP BTB domain complexed with the Cul3 N-terminal domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | Speckle-type POZ protein | polymer | 145 | 16167.5 | 2 | UniProt (O43791) Pfam (PF00651) | Homo sapiens (human) | HIB homolog 1, Roadkill homolog 1 |
| 2 | C, D (B, D) | Cullin-3 | polymer | 364 | 43461.7 | 2 | UniProt (Q13618) Pfam (PF00888) | Homo sapiens (human) | CUL-3 |
| 3 | E, F, G, H (A, C, B, D) | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
A, C: 177 - 319 (UniProt: O43791)
B, D: 20 - 381 (UniProt: Q13618)
| PDB | External Database | Details |
|---|---|---|
| Gly 175 | - | expression tag |
| Ser 176 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 18 | - | expression tag |
| Ser 19 | - | expression tag |
| Arg 342 | Ile 342 | engineered mutation |
| Asp 346 | Leu 346 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 119258.5 | |
| All* | Total formula weight | 119258.5 |
