4EOO
Thr 160 phosphorylated CDK2 Q131E - human cyclin A3 complex with ATP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | Cyclin-dependent kinase 2 | polymer | 299 | 34088.4 | 2 | UniProt (P24941) Pfam (PF00069) In PDB | Homo sapiens (human) | Cell division protein kinase 2, p33 protein kinase |
| 2 | B, D | Cyclin-A2 | polymer | 258 | 29624.3 | 2 | UniProt (P20248) Pfam (PF00134) Pfam (PF02984) In PDB | Homo sapiens (human) | Cyclin-A |
| 3 | A, B, C | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 4 | A, C | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 5 | B, D | MONOTHIOGLYCEROL | non-polymer | 108.2 | 2 | Chemie (SGM) | |||
| 6 | water | water | 18.0 | 433 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 297 (UniProt: P24941)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | EXPRESSION TAG |
| Ser 0 | - | EXPRESSION TAG |
| Glu 131 | Gln 131 | ENGINEERED MUTATION |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 127425.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1303.6 | |
| All* | Total formula weight | 128729.0 |
