4EN3
Crystal structure of a human Valpha24(-) NKT TCR in complex with CD1d/alpha-galactosylceramide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | C | Antigen-presenting glycoprotein CD1d | polymer | 284 | 32366.4 | 1 | UniProt (P15813) Pfam (PF16497) Pfam (PF07654) In PDB | Homo sapiens (human) | R3G1 |
2 | A | HUMAN NKT TCR ALPHA CHAIN | polymer | 220 | 24517.0 | 1 | Pfam (PF07686) Pfam (PF09291) UniProt (by SIFTS) (K7N5M3) In PDB | Homo sapiens (human) | |
3 | B | HUMAN NKT TCR BETA CHAIN | polymer | 259 | 29319.5 | 1 | Pfam (PF07686) Pfam (PF07654) UniProt (by SIFTS) (K7N5M4) In PDB | Homo sapiens (human) | Beta-2-microglobulin form pI 5.3 |
4 | D | Beta-2-microglobulin | polymer | 100 | 11845.3 | 1 | UniProt (P61769) Pfam (PF07654) In PDB | Homo sapiens (human) | |
5 | C, A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
6 | C | N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE | non-polymer | 858.3 | 1 | Chemie (AGH) | |||
7 | A | alpha-L-fucopyranose | non-polymer | 164.2 | 1 | Chemie (FUC) | |||
8 | B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
9 | water | water | 18.0 | 101 | Chemie (HOH) |
Sequence modifications
C: 3 - 277 (UniProt: P15813)
D: 1 - 99 (UniProt: P61769)
PDB | External Database | Details |
---|---|---|
Ala 0 | - | expression tag |
Asp 1 | - | expression tag |
Pro 2 | - | expression tag |
His 278 | - | expression tag |
His 279 | - | expression tag |
His 280 | - | expression tag |
His 281 | - | expression tag |
His 282 | - | expression tag |
His 283 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Pro 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 98048.2 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 2312.7 | |
All* | Total formula weight | 100360.9 |