4EKW

Crystal structure of the NavAb voltage-gated sodium channel (wild-type, 3.2 A)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Ion transport protein	polymer	285	33724.7	4	UniProt (A8EVM5) Pfam (PF00520) In PDB	Arcobacter butzleri
2	A, B, C, D	1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE	non-polymer		678.9	5	Chemie (PX4)
3	A, B, C, D	PHOSPHATE ION	non-polymer		95.0	4	Chemie (PO4)
4		water	water		18.0	3	Chemie (HOH)

Sequence modifications

A, B, C, D: 1001 - 1267 (UniProt: A8EVM5)

PDB	External Database	Details
Mse 983	-	initiating methionine
Asp 984	-	expression tag
Tyr 985	-	expression tag
Lys 986	-	expression tag
Asp 987	-	expression tag
Asp 988	-	expression tag
Asp 989	-	expression tag
Asp 990	-	expression tag
Lys 991	-	expression tag
Gly 992	-	expression tag
Ser 993	-	expression tag
Leu 994	-	expression tag
Val 995	-	expression tag
Pro 996	-	expression tag
Arg 997	-	expression tag
Gly 998	-	expression tag
Ser 999	-	expression tag
His 1000	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	134898.9
Non-Polymers*	Number of molecules	9
	Total formula weight	3774.6
All*	Total formula weight	138673.5

*Water molecules are not included.