4EJG

Human Cytochrome P450 2A13 in complex with Nicotine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Cytochrome P450 2A13	polymer	476	54804.8	8	UniProt (Q16696) Pfam (PF00067) In PDB	Homo sapiens (human)	CYPIIA13
2	A, B, C, D, E...	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	8	Chemie (HEM)
3	A, B, C, D	(S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE	non-polymer		162.2	4	Chemie (NCT)
4	H	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5		water	water		18.0	49	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 31 - 494 (UniProt: Q16696)

PDB	External Database	Details
Met 23	-	expression tag
Ala 24	-	expression tag
Lys 25	-	expression tag
Lys 26	-	expression tag
Thr 27	-	expression tag
Ser 28	-	expression tag
Ser 29	-	expression tag
Lys 30	-	expression tag
His 495	-	expression tag
His 496	-	expression tag
His 497	-	expression tag
His 498	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	438438.1
Non-Polymers*	Number of molecules	13
	Total formula weight	5672.9
All*	Total formula weight	444111.0

*Water molecules are not included.