4EHT

Activator of the 2-Hydroxyisocaproyl-CoA dehydratase from Clostridium difficile with bound ADP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Activator of 2-hydroxyisocaproyl-CoA dehydratase	polymer	276	29655.9	2	UniProt (Q5U925) Pfam (PF01869)	Clostridium difficile
2	C (A)	IRON/SULFUR CLUSTER	non-polymer		351.6	1	Chemie (SF4)
3	D, J (A, B)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
4	E, K (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5	F, G, L (A, B)	ACETATE ION	non-polymer		59.0	3	Chemie (ACT)
6	H, I (A)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
7	M (B)	AMMONIUM ION	non-polymer		18.0	1	Chemie (NH4)
8	N, O (A, B)	water	water		18.0	271	Chemie (HOH)

Sequence modifications

A, B: 1 - 266 (UniProt: Q5U925)

PDB	External Database	Details
Ser 267	-	expression tag
Ala 268	-	expression tag
Trp 269	-	expression tag
Ser 270	-	expression tag
His 271	-	expression tag
Pro 272	-	expression tag
Gln 273	-	expression tag
Phe 274	-	expression tag
Glu 275	-	expression tag
Lys 276	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	59311.7
Non-Polymers*	Number of molecules	11
	Total formula weight	1520.7
All*	Total formula weight	60832.4

*Water molecules are not included.