4EH9
Human p38 MAP kinase in complex with NP-F11 and RL87
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 14 | polymer | 360 | 41269.1 | 1 | UniProt (Q16539) Pfam (PF00069) | Homo sapiens (human) | MAP kinase 14, MAPK 14, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAP kinase MXI2, MAX-interacting protein 2, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Stress-activated protein kinase 2a, SAPK2a |
| 2 | B (A) | N~4~-cyclopropyl-2-phenylquinazoline-4,7-diamine | non-polymer | 276.3 | 1 | Chemie (IRG) | |||
| 3 | C (A) | (1R,5S)-3-[4-(trifluoromethyl)benzoyl]-1,2,3,4,5,6-hexahydro-8H-1,5-methanopyrido[1,2-a][1,5]diazocin-8-one | non-polymer | 362.3 | 1 | Chemie (0OQ) | |||
| 4 | D (A) | water | water | 18.0 | 61 | Chemie (HOH) |
Sequence modifications
A: 2 - 360 (UniProt: Q16539)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41269.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 638.7 | |
| All* | Total formula weight | 41907.7 |
