4EFG

Crystal Structure of the Q108K:K40L:T51V:T53C:Y19W:R58W:T29L Mutant of Cellular Retinol Binding Protein Type II in Complex with All-trans-Retinal at 1.58 Angstrom Resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Retinol-binding protein 2	polymer	133	15646.7	2	UniProt (P50120) Pfam (PF00061) In PDB	Homo sapiens (human)	Cellular retinol-binding protein II, CRBP-II
2	A, B	RETINAL	non-polymer		284.4	2	Chemie (RET)
3	A, B	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
4		water	water		18.0	238	Chemie (HOH)

Sequence modifications

A, B: 1 - 133 (UniProt: P50120)

PDB	External Database	Details
Trp 19	Tyr 20	engineered mutation
Leu 29	Thr 30	engineered mutation
Leu 40	Lys 41	engineered mutation
Val 51	Thr 52	engineered mutation
Cys 53	Thr 54	engineered mutation
Trp 58	Arg 59	engineered mutation
Lys 108	Gln 109	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	31293.3
Non-Polymers*	Number of molecules	4
	Total formula weight	687.0
All*	Total formula weight	31980.3

*Water molecules are not included.