4EEQ
Crystal structure of E. faecalis DNA ligase with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA ligase | polymer | 331 | 37933.6 | 1 | UniProt (Q837V6) Pfam (PF01653) | Enterococcus faecalis | Polydeoxyribonucleotide synthase [NAD(+)] |
| 2 | B, C (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | D (A) | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE | non-polymer | 335.2 | 1 | Chemie (NMN) | |||
| 4 | E (A) | 4-amino-2-(cyclopentyloxy)pyrimidine-5-carboxamide | non-polymer | 222.2 | 1 | Chemie (0OX) | |||
| 5 | F (A) | water | water | 18.0 | 440 | Chemie (HOH) |
Sequence modifications
A: 1 - 324 (UniProt: Q837V6)
| PDB | External Database | Details |
|---|---|---|
| Leu 324 | Val 324 | conflict |
| Glu 325 | - | expression tag |
| His 326 | - | expression tag |
| His 327 | - | expression tag |
| His 328 | - | expression tag |
| His 329 | - | expression tag |
| His 330 | - | expression tag |
| His 331 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37933.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 749.6 | |
| All* | Total formula weight | 38683.2 |
