4EE0
Crystal structure of hH-PGDS with water displacing inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Hematopoietic prostaglandin D synthase | polymer | 199 | 23377.8 | 2 | UniProt (O60760) Pfam (PF02798) Pfam (PF14497) In PDB | Homo sapiens (human) | H-PGDS, GST class-sigma, Glutathione S-transferase, Glutathione-dependent PGD synthase, Glutathione-requiring prostaglandin D synthase, Prostaglandin-H2 D-isomerase |
| 2 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | A, B | 4-(isoquinolin-1-yl)-N-[2-(morpholin-4-yl)ethyl]benzamide | non-polymer | 361.4 | 2 | Chemie (0O4) | |||
| 4 | A, B | L-GAMMA-GLUTAMYL-3-SULFINO-L-ALANYLGLYCINE | non-polymer | 339.3 | 2 | Chemie (GSF) | |||
| 5 | water | water | 18.0 | 307 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 199 (UniProt: O60760)
| PDB | External Database | Details |
|---|---|---|
| His 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46755.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1425.8 | |
| All* | Total formula weight | 48181.4 |
