4EDY
Crystal structure of hH-PGDS with water displacing inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Hematopoietic prostaglandin D synthase | polymer | 199 | 23377.8 | 2 | UniProt (O60760) Pfam (PF02798) Pfam (PF14497) | Homo sapiens (human) | H-PGDS, GST class-sigma, Glutathione S-transferase, Glutathione-dependent PGD synthase, Glutathione-requiring prostaglandin D synthase, Prostaglandin-H2 D-isomerase |
| 2 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | D, G (A, B) | GLUTATHIONE | non-polymer | 307.3 | 2 | Chemie (GSH) | |||
| 4 | E (A) | 4-[2-(hydroxymethyl)naphthalen-1-yl]-N-[2-(morpholin-4-yl)ethyl]benzamide | non-polymer | 390.5 | 1 | Chemie (9PQ) | |||
| 5 | F (B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 6 | H, I (A, B) | water | water | 18.0 | 684 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 199 (UniProt: O60760)
| PDB | External Database | Details |
|---|---|---|
| His 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46755.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1107.6 | |
| All* | Total formula weight | 47863.1 |
