4EDW
Nerve Growth Factor in Complex with Fab from humanized version of mouse mAb 911 (tanezumab)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (V) | Beta-nerve growth factor | polymer | 120 | 13515.4 | 1 | UniProt (P01138) Pfam (PF00243) | Homo sapiens (human) | Beta-NGF |
| 2 | B (L) | tanezumab Fab light chain | polymer | 214 | 23621.2 | 1 | Homo sapiens | ||
| 3 | C (H) | tanezumab Fab heavy chain | polymer | 231 | 24959.7 | 1 | Homo sapiens | ||
| 4 | D (H) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E, F, G (V, L, H) | water | water | 18.0 | 37 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 62096.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 62188.4 |
