4EDA

Structures of monomeric hemagglutinin and its complex with an Fab fragment of a neutralizing antibody that binds to H1 subtype influenza viruses: molecular basis of infectivity of 2009 pandemic H1N1 influenza A viruses

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Hemagglutinin	polymer	336	37341.1	2	UniProt (C5MQE6) Pfam (PF00509)	Influenza A virus
2	B, D (B, D)	Hemagglutinin	polymer	182	20844.1	2	UniProt (C5MQE6) Pfam (PF00509)	Influenza A virus
3	E, F (E, F)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
4	G, H, I, J (A, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
5	K, L, M, N (A, B, C, D)	water	water		18.0	63	Chemie (HOH)

Sequence modifications

A, C: 1 - 327 (UniProt: C5MQE6)

PDB	External Database	Details
Ala -8	-	expression tag
Asp -7	-	expression tag
Pro -6	-	expression tag
Gly -5	-	expression tag
Tyr -4	-	expression tag
Leu -3	-	expression tag
Leu -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag

B, D: 1 - 176 (UniProt: C5MQE6)

PDB	External Database	Details
Arg 177	-	expression tag
Ser 178	-	expression tag
Leu 179	-	expression tag
Val 180	-	expression tag
Pro 181	-	expression tag
Arg 182	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	116370.4
Branched	Number of molecules	2
	Total formula weight	848.8
Non-Polymers*	Number of molecules	4
	Total formula weight	884.8
All*	Total formula weight	118104.0

*Water molecules are not included.