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4ED6

Human DNA polymerase eta - DNA ternary complex: Reaction in the AT crystal at pH 6.7 for 15 hr, Sideway translocation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase etapolymer43548617.71UniProt (Q9Y253)
Pfam (PF00817)
Pfam (PF21704)
Pfam (PF11799)
Homo sapiens (human)RAD30 homolog A, Xeroderma pigmentosum variant type protein
2B
(T)
DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3')polymer123637.41
3C
(P)
DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3')polymer92739.81
4D, E
(A)
GLYCEROLnon-polymer92.12Chemie (GOL)
5F, G, H
(A, T, P)
waterwater18.0225Chemie (HOH)
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight54994.9
Non-Polymers*Number of molecules2
Total formula weight184.2
All*Total formula weight55179.1
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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