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4ECT

Human DNA polymerase eta - DNA ternary complex: Reaction in the AT crystal at pH 7.0 for 140 sec

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADNA polymerase etapolymer43548617.71UniProt (Q9Y253)
Pfam (PF00817)
Pfam (PF21704)
Pfam (PF11799)
In PDB
Homo sapiens (human)RAD30 homolog A, Xeroderma pigmentosum variant type protein
2TDNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3')polymer123637.41
3PDNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3')polymer92739.81
4A, PMAGNESIUM IONnon-polymer24.33Chemie (MG)
5ACALCIUM IONnon-polymer40.11Chemie (CA)
6AGLYCEROLnon-polymer92.13Chemie (GOL)
7P2'-DEOXYADENOSINE 5'-TRIPHOSPHATEnon-polymer491.21Chemie (DTP)
8PDIPHOSPHATEnon-polymer173.91Chemie (DPO)
9waterwater18.0542Chemie (HOH)
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight54994.9
Non-Polymers*Number of molecules9
Total formula weight1054.4
All*Total formula weight56049.3
*Water molecules are not included.

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PDB entries from 2024-04-17

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