4EC0
Crystal structure of hH-PGDS with water displacing inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Hematopoietic prostaglandin D synthase | polymer | 200 | 23509.0 | 2 | UniProt (O60760) Pfam (PF02798) Pfam (PF14497) In PDB | Homo sapiens (human) | H-PGDS, GST class-sigma, Glutathione S-transferase, Glutathione-dependent PGD synthase, Glutathione-requiring prostaglandin D synthase, Prostaglandin-H2 D-isomerase |
| 2 | A, B | GLUTATHIONE | non-polymer | 307.3 | 2 | Chemie (GSH) | |||
| 3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | A | 4-[2-(aminomethyl)naphthalen-1-yl]-N-[2-(morpholin-4-yl)ethyl]benzamide | non-polymer | 389.5 | 1 | Chemie (7PQ) | |||
| 5 | water | water | 18.0 | 761 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 199 (UniProt: O60760)
| PDB | External Database | Details |
|---|---|---|
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47018.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1028.4 | |
| All* | Total formula weight | 48046.4 |
