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4EBL

BlaC E166A Faropenem Acyl-Intermediate Complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Beta-lactamasepolymer26528214.74UniProt (P0C5C1)
Pfam (PF00144)
Pfam (PF13354)
UniProt (by SIFTS) (P9WKD3)
Mycobacterium tuberculosisPenicillinase
2E, F, G, H, J...
(A, B, C, D)
PHOSPHATE IONnon-polymer95.08Chemie (PO4)
3I, L
(B, C)
(2R,5R)-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-5-[(2R)-tetrahydrofuran-2-yl]-2,5-dihydro-1,3-thiazole-4-carboxylic acidnon-polymer287.32Chemie (DGF)
4O, P, Q, R
(A, B, C, D)
waterwater18.0428Chemie (HOH)
Sequence modifications
A, B, C, D: 29 - 293 (UniProt: P0C5C1)
PDBExternal DatabaseDetails
Ala 166Glu 182ENGINEERED MUTATION
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight112858.8
Non-Polymers*Number of molecules10
Total formula weight1334.4
All*Total formula weight114193.2
*Water molecules are not included.

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PDB entries from 2024-11-13

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