4EB9
cIAP1-BIR3 in complex with a divalent Smac mimetic
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Baculoviral IAP repeat-containing protein 2 | polymer | 122 | 14390.2 | 4 | UniProt (Q13490) Pfam (PF00653) In PDB | Homo sapiens (human) | C-IAP1, IAP homolog B, Inhibitor of apoptosis protein 2, IAP-2, hIAP-2, hIAP2, RING finger protein 48, TNFR2-TRAF-signaling complex protein 2 |
2 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
3 | C, D | (3S,6S,7S,9aS,3'S,6'S,7'S,9a'S)-N,N'-(benzene-1,4-diylbis{butane-4,1-diyl-1H-1,2,3-triazole-1,4-diyl[(S)-phenylmethanediyl]})bis[7-(hydroxymethyl)-6-{[(2S)-2-(methylamino)butanoyl]amino}-5-oxooctahydro-1H-pyrrolo[1,2-a]azepine-3-carboxamide] | non-polymer | 1181.5 | 2 | Chemie (0O6) | |||
4 | water | water | 18.0 | 111 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 245 - 357 (UniProt: Q13490)
PDB | External Database | Details |
---|---|---|
Met 244 | - | initiating methionine |
Leu 358 | - | expression tag |
Glu 359 | - | expression tag |
His 360 | - | expression tag |
His 361 | - | expression tag |
His 362 | - | expression tag |
His 363 | - | expression tag |
His 364 | - | expression tag |
His 365 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 57561.0 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 2624.6 | |
All* | Total formula weight | 60185.5 |