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4E8A

The crystal structure of p38a MAP kinase in complex with PIA24

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Mitogen-activated protein kinase 14polymer36041343.21UniProt (Q16539)
Pfam (PF00069)
Homo sapiens (human)MAP kinase 14, MAPK 14, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAP kinase MXI2, MAX-interacting protein 2, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Stress-activated protein kinase 2a, SAPK2a
2B
(A)
(1R,2S,3R,4S,6S)-6-(cyclohexylmethoxy)-2,3,4-trihydroxycyclohexyl (2R)-2-methoxy-3-(octadecyloxy)propyl hydrogen (S)-phosphatenon-polymer680.91Chemie (0OA)
3C
(A)
waterwater18.09Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41343.2
Non-Polymers*Number of molecules1
Total formula weight680.9
All*Total formula weight42024.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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