4E7S

Myosin VI D23R I24R R569E (MD) pre-powerstroke state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Myosin-VI	polymer	798	91090.5	2	UniProt (F1RQI7) Pfam (PF00063) In PDB	Sus scrofa (pigs swine wild boar)
2	A, B	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
3	A, B	VANADATE ION	non-polymer		114.9	2	Chemie (VO4)
4	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5	A, B	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
6	B	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
7		water	water		18.0	469	Chemie (HOH)

Sequence modifications

A, B: 2 - 789 (UniProt: F1RQI7)

PDB	External Database	Details
Met -8	-	expression tag
Asp -7	-	expression tag
Tyr -6	-	expression tag
Lys -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Lys 0	-	expression tag
Gly 1	-	expression tag
Arg 23	Asp 23	engineered mutation
Arg 24	Ile 24	engineered mutation
Glu 569	Arg 569	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	182180.9
Non-Polymers*	Number of molecules	13
	Total formula weight	1780.4
All*	Total formula weight	183961.3

*Water molecules are not included.