4E76
Apo crystal structure of HCV NS5B genotype 2A JFH-1 isolate with beta hairpin loop deletion
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | RNA-directed RNA polymerase | polymer | 572 | 63736.2 | 1 | UniProt (Q99IB8) Pfam (PF00998) In PDB | Hepatitis C virus (HCV) | NS5B, p68 |
2 | A | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
4 | water | water | 18.0 | 169 | Chemie (HOH) |
Sequence modifications
A: 1 - 443 (UniProt: Q99IB8)
A: 454 - 570 (UniProt: Q99IB8)
PDB | External Database | Details |
---|---|---|
Met -1 | - | expression tag |
Ser 0 | - | expression tag |
Gln 86 | Glu 2528 | engineered mutation |
Gln 87 | Glu 2529 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 444 | - | linker |
Gly 445 | - | linker |
Leu 571 | - | expression tag |
Glu 572 | - | expression tag |
His 573 | - | expression tag |
His 574 | - | expression tag |
His 575 | - | expression tag |
His 576 | - | expression tag |
His 577 | - | expression tag |
His 578 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 63736.2 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 734.5 | |
All* | Total formula weight | 64470.7 |