Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

4E76

Apo crystal structure of HCV NS5B genotype 2A JFH-1 isolate with beta hairpin loop deletion

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
RNA-directed RNA polymerasepolymer57263736.21UniProt (Q99IB8)
Pfam (PF00998)
Hepatitis C virus (HCV)NS5B, p68
2B, C, D, E, F...
(A)
SULFATE IONnon-polymer96.17Chemie (SO4)
3I
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
4J
(A)
waterwater18.0169Chemie (HOH)
Sequence modifications
A: 1 - 443 (UniProt: Q99IB8)
PDBExternal DatabaseDetails
Met -1-expression tag
Ser 0-expression tag
Gln 86Glu 2528engineered mutation
Gln 87Glu 2529engineered mutation
A: 454 - 570 (UniProt: Q99IB8)
PDBExternal DatabaseDetails
Gly 444-linker
Gly 445-linker
Leu 571-expression tag
Glu 572-expression tag
His 573-expression tag
His 574-expression tag
His 575-expression tag
His 576-expression tag
His 577-expression tag
His 578-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight63736.2
Non-Polymers*Number of molecules8
Total formula weight734.5
All*Total formula weight64470.7
*Water molecules are not included.

238582

PDB entries from 2025-07-09

PDB statisticsPDBj update infoContact PDBjnumon