4E5Z

Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	DNA damage-binding protein 1	polymer	1150	128478.9	1	UniProt (Q16531) Pfam (PF10433) Pfam (PF03178) In PDB	Homo sapiens (human)	DDB p127 subunit, DNA damage-binding protein a, DDBa, Damage-specific DNA-binding protein 1, HBV X-associated protein 1, XAP-1, UV-damaged DNA-binding factor, UV-damaged DNA-binding protein 1, UV-DDB 1, XPE-binding factor, XPE-BF, Xeroderma pigmentosum group E-complementing protein, XPCe
2	B	DNA damage-binding protein 2	polymer	436	49059.0	1	UniProt (Q92466) Pfam (PF00400) In PDB	Homo sapiens (human)	DDB p48 subunit, DDBb, Damage-specific DNA-binding protein 2, UV-damaged DNA-binding protein 2, UV-DDB 2
3	F	AP24 DNA strand	polymer	24	7424.8	1
4	G	AP24 DNA complementary strand	polymer	24	7189.6	1

Sequence modifications

A: 2 - 1140 (UniProt: Q16531)

PDB	External Database	Details
Met -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag

B: 2 - 428 (UniProt: Q92466)

PDB	External Database	Details
Met -7	-	expression tag
Asp -6	-	expression tag
Tyr -5	-	expression tag
Lys -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Asp 0	-	expression tag
Lys 1	-	expression tag
Glu 420	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	192152.4
All*	Total formula weight	192152.4

*Water molecules are not included.