4E5J

Crystal structure of avian influenza virus PAn bound to compound 5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Polymerase protein PA	polymer	187	21916.0	4	UniProt (Q5EP34)	Influenza A virus	polymerase acidic protein
2	E, F, K, L, Q... (A, B, C, D)	SULFATE ION	non-polymer		96.1	8	Chemie (SO4)
3	G, H, M, N, S... (A, B, C, D)	2-[3-(acetylamino)phenyl]-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid	non-polymer		289.2	8	Chemie (581)
4	AA, BA, I, J, O... (D, A, B, C)	MANGANESE (II) ION	non-polymer		54.9	8	Chemie (MN)
5	CA, DA, EA, FA (A, B, C, D)	water	water		18.0	47	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 50 (UniProt: Q5EP34)
A, B, C, D: 73 - 196 (UniProt: Q5EP34)

PDB	External Database	Details
Gly 50	-	linker
Gly 50	-	linker
Ser 50	-	linker
Ala 197	-	expression tag
Ala 198	-	expression tag
Ala 199	-	expression tag
Glu 200	-	expression tag
Leu 201	-	expression tag
Ala 202	-	expression tag
Leu 203	-	expression tag
Val 204	-	expression tag
Pro 205	-	expression tag
Arg 206	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	87663.8
Non-Polymers*	Number of molecules	24
	Total formula weight	3522.0
All*	Total formula weight	91185.8

*Water molecules are not included.