4E5G

Crystal structure of avian influenza virus PAn bound to compound 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Polymerase protein PA	polymer	187	21916.0	4	UniProt (Q5EP34)	Influenza A virus	polymerase acidic protein
2	E, F, K, L, Q... (A, B, C, D)	SULFATE ION	non-polymer		96.1	8	Chemie (SO4)
3	G, H, M, N, S... (A, B, C, D)	MANGANESE (II) ION	non-polymer		54.9	8	Chemie (MN)
4	AA, BA, I, J, O... (D, A, B, C)	2-4-DIOXO-4-PHENYLBUTANOIC ACID	non-polymer		192.2	8	Chemie (XI7)
5	CA, DA, EA, FA (A, B, C, D)	water	water		18.0	9	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 50 (UniProt: Q5EP34)
A, B, C, D: 73 - 196 (UniProt: Q5EP34)

PDB	External Database	Details
Gly 50	-	linker
Gly 50	-	linker
Ser 50	-	linker
Ala 196	-	expression tag
Ala 196	-	expression tag
Ala 196	-	expression tag
Glu 196	-	expression tag
Leu 197	-	expression tag
Ala 198	-	expression tag
Leu 199	-	expression tag
Val 200	-	expression tag
Pro 201	-	expression tag
Arg 202	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	87663.8
Non-Polymers*	Number of molecules	24
	Total formula weight	2745.4
All*	Total formula weight	90409.2

*Water molecules are not included.