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4E4Q

Crystal structure of PPARgamma with the ligand FS214

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BPeroxisome proliferator-activated receptor gammapolymer28732693.82UniProt (P37231)
Pfam (PF00104)
In PDB
Homo sapiens (human)PPAR-gamma, Nuclear receptor subfamily 1 group C member 3
2A(2R)-3-phenyl-2-{[2'-(propan-2-yl)biphenyl-4-yl]oxy}propanoic acidnon-polymer360.41Chemie (RRH)
3waterwater18.0140Chemie (HOH)
Sequence modifications
A, B: 195 - 477 (UniProt: P37231)
PDBExternal DatabaseDetails
Gly 191-expression tag
Ser 192-expression tag
His 193-expression tag
Met 194-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight65387.6
Non-Polymers*Number of molecules1
Total formula weight360.4
All*Total formula weight65748.1
*Water molecules are not included.

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PDB entries from 2024-09-18

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