4E4Q
Crystal structure of PPARgamma with the ligand FS214
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peroxisome proliferator-activated receptor gamma | polymer | 287 | 32693.8 | 2 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (human) | PPAR-gamma, Nuclear receptor subfamily 1 group C member 3 |
| 2 | C (A) | (2R)-3-phenyl-2-{[2'-(propan-2-yl)biphenyl-4-yl]oxy}propanoic acid | non-polymer | 360.4 | 1 | Chemie (RRH) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 140 | Chemie (HOH) |
Sequence modifications
A, B: 195 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Gly 191 | - | expression tag |
| Ser 192 | - | expression tag |
| His 193 | - | expression tag |
| Met 194 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65387.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 360.4 | |
| All* | Total formula weight | 65748.1 |
