4E3J

Crystal structure of AmpC beta-lactamase in complex with a designed 4-tetrazolyl benzene sulfonamide boronic acid inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Beta-lactamase	polymer	358	39587.9	2	UniProt (P00811) Pfam (PF00144)	Escherichia coli	Cephalosporinase
2	C, E (A, B)	[({[4-(1H-tetrazol-5-yl)phenyl]sulfonyl}amino)methyl]boronic acid	non-polymer		283.1	2	Chemie (0N4)
3	D, F (A, B)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
4	G, H (A, B)	water	water		18.0	446	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	79175.8
Non-Polymers*	Number of molecules	4
	Total formula weight	756.1
All*	Total formula weight	79931.9

*Water molecules are not included.