4E33

X-ray Structure of the C-3'-Methyltransferase TcaB9 in Complex with S-Adenosyl-L-Homocysteine and Reduced dTDP-Sugar Substrate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	TcaB9	polymer	416	46090.9	1	UniProt (B5L6K6)	Micromonospora chalcea	C-3'-Methyltransferase
2	B (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
3	C (A)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	1	Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (13792) PubChem (177678424) PubChem (189149) PubChem (439155) PubChem (25210495) PubChem (21125603) PubChem (44361184) PubChem (25203782) PubChem (46936206) PubChem (50989525) PubChem (51380914) PubChem (52224398) PubChem (57544532) PubChem (52224400) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (5284331) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (71170554) PubChem (13231890) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (126969526) PubChem (129105892) PubChem (164157219) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525)
4	D (A)	(2R,4S,5R,6R)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate	non-polymer		531.3	1	Chemie (0N2) PubChem (177505636) PubChem (23250405) PubChem (45479250) PubChem (46174036) PubChem (56947177) PubChem (443839) PubChem (102016858) PubChem (162822455) PubChem (162822456)
5	E (A)	water	water		18.0	402	Chemie (HOH)

Sequence modifications

A: 1 - 414 (UniProt: B5L6K6)

PDB	External Database	Details
Gly -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	46090.9
Non-Polymers*	Number of molecules	3
	Total formula weight	981.2
All*	Total formula weight	47072.1

*Water molecules are not included.