4DZ3
Crystal structure of a Peptidyl-prolyl cis-trans isomerase with surface mutation M61H from Burkholderia pseudomallei complexed with FK506
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peptidyl-prolyl cis-trans isomerase | polymer | 113 | 11904.2 | 2 | UniProt (Q3JK38) Pfam (PF00254) | Burkholderia pseudomallei | |
| 2 | C, I (A, B) | 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN | non-polymer | 804.0 | 2 | Chemie (FK5) | |||
| 3 | D, J (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | E, F, G, K, L... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 5 | H, N, O, P, Q (A, B) | ACETATE ION | non-polymer | 59.0 | 5 | Chemie (ACT) | |||
| 6 | R, S (A, B) | water | water | 18.0 | 131 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 113 (UniProt: Q3JK38)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| His 61 | Met 61 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 23808.5 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 2355.8 | |
| All* | Total formula weight | 26164.3 |
