4DZ3
Crystal structure of a Peptidyl-prolyl cis-trans isomerase with surface mutation M61H from Burkholderia pseudomallei complexed with FK506
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peptidyl-prolyl cis-trans isomerase | polymer | 113 | 11904.2 | 2 | UniProt (Q3JK38) | Burkholderia pseudomallei | |
| 2 | C, I (A, B) | 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN | non-polymer | 804.0 | 2 | Chemie (FK5) PubChem (23377000) PubChem (177746942) PubChem (403209) PubChem (439492) PubChem (23308325) PubChem (23581796) PubChem (24978521) PubChem (44294761) PubChem (44314852) PubChem (44575549) PubChem (46783859) PubChem (46781577) PubChem (54611630) PubChem (57206900) PubChem (49874294) PubChem (59042420) PubChem (59111253) PubChem (59112447) PubChem (59118415) PubChem (59746606) PubChem (59917266) PubChem (59918741) PubChem (60086106) PubChem (57417278) PubChem (66509027) PubChem (66672804) PubChem (57892354) PubChem (57910335) PubChem (58584114) PubChem (59032416) PubChem (58946030) PubChem (59141120) PubChem (59049316) PubChem (59974193) PubChem (59993548) PubChem (60035606) PubChem (66709866) PubChem (67340654) PubChem (67626881) PubChem (71296869) PubChem (71316759) PubChem (5353987) PubChem (68219140) PubChem (68712665) PubChem (69247758) PubChem (71668407) PubChem (176478128) PubChem (5472317) PubChem (176856280) PubChem (177675132) PubChem (73265325) PubChem (5372) PubChem (64779) PubChem (6536850) PubChem (89068341) PubChem (6610362) PubChem (6912836) PubChem (445643) PubChem (9940643) PubChem (77906388) PubChem (89249909) PubChem (89545901) PubChem (89960652) PubChem (13819073) PubChem (145857191) PubChem (117646237) PubChem (6426916) PubChem (6436007) PubChem (6473866) PubChem (123552884) PubChem (9832283) PubChem (9853905) PubChem (125039862) PubChem (9918805) PubChem (125136698) PubChem (125136697) PubChem (9963169) PubChem (129009965) PubChem (129010422) PubChem (130330191) PubChem (131676819) PubChem (133562888) PubChem (133688365) PubChem (11556866) PubChem (134694629) PubChem (12134936) PubChem (124511204) PubChem (13006299) PubChem (125039860) PubChem (125039861) PubChem (125136699) PubChem (125136700) PubChem (125182986) PubChem (137705868) PubChem (138106951) PubChem (138574020) PubChem (126687738) PubChem (129606865) PubChem (140494820) PubChem (13819070) PubChem (140647114) PubChem (13819074) PubChem (13819069) PubChem (140893615) PubChem (131668141) PubChem (149048732) PubChem (160433486) PubChem (162711219) PubChem (163027397) PubChem (163027399) PubChem (163027400) PubChem (137546410) PubChem (137546581) PubChem (138574025) PubChem (139032034) PubChem (166023667) PubChem (140652196) PubChem (168312998) PubChem (143265740) PubChem (144640477) PubChem (146323807) PubChem (170277719) PubChem (171042252) PubChem (171360199) PubChem (156417380) PubChem (156528350) PubChem (172042935) PubChem (160433487) PubChem (173882479) PubChem (163027398) PubChem (163027401) PubChem (163027402) PubChem (167413568) PubChem (170997009) PubChem (171122179) PubChem (171137683) PubChem (171156312) PubChem (171322980) PubChem (171329370) PubChem (172634670) PubChem (175667550) | |||
| 3 | D, J (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) PubChem (271) | |||
| 4 | E, F, G, K, L... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 5 | H, N, O, P, Q (A, B) | ACETATE ION | non-polymer | 59.0 | 5 | Chemie (ACT) PubChem (175) | |||
| 6 | R, S (A, B) | water | water | 18.0 | 131 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 113 (UniProt: Q3JK38)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| His 61 | Met 61 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 23808.5 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 2355.8 | |
| All* | Total formula weight | 26164.3 |
