4DZ0
Crystal structure of the Cu-adduct of human H-Ferritin variant MIC1 labeled with a dansyl fluorophore
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Ferritin heavy chain | polymer | 172 | 20021.2 | 1 | UniProt (P02794) Pfam (PF00210) In PDB | Homo sapiens (human) | Ferritin H subunit, Cell proliferation-inducing gene 15 protein |
2 | A | 5-(1-SULFONAPHTHYL)-ACETYLAMINO-ETHYLAMINE | non-polymer | 308.4 | 1 | Chemie (AEN) | |||
3 | A | COPPER (II) ION | non-polymer | 63.5 | 3 | Chemie (CU) | |||
4 | A | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
5 | water | water | 18.0 | 51 | Chemie (HOH) |
Sequence modifications
A: 5 - 176 (UniProt: P02794)
PDB | External Database | Details |
---|---|---|
Glu 39 | Tyr 40 | conflict |
Cys 53 | Lys 54 | engineered mutation |
His 56 | Leu 57 | engineered mutation |
His 63 | Arg 64 | engineered mutation |
His 67 | Glu 68 | engineered mutation |
Glu 74 | Asn 75 | conflict |
Gln 86 | Lys 87 | engineered mutation |
Ala 88 | Pro 89 | conflict |
Glu 90 | Cys 91 | engineered mutation |
Ala 102 | Cys 103 | engineered mutation |
Ala 130 | Cys 131 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 20021.2 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 619.2 | |
All* | Total formula weight | 20640.4 |