4DYX

Crystal Structure of the Cu-adduct of Human H-Ferritin variant 4His-delta C-star

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Ferritin heavy chain	polymer	172	20092.3	1	UniProt (P02794) Pfam (PF00210) In PDB	Homo sapiens (human)	Ferritin H subunit, Cell proliferation-inducing gene 15 protein
2	A	COPPER (II) ION	non-polymer		63.5	4	Chemie (CU)
3	A	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
4		water	water		18.0	215	Chemie (HOH)

Sequence modifications

A: 5 - 176 (UniProt: P02794)

PDB	External Database	Details
His 56	Leu 57	conflict
His 63	Arg 64	conflict
His 67	Glu 68	conflict
Gln 86	Lys 87	engineered mutation
Glu 90	Cys 91	engineered mutation
Ala 102	Cys 103	engineered mutation
Ala 130	Cys 131	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	20092.3
Non-Polymers*	Number of molecules	7
	Total formula weight	374.4
All*	Total formula weight	20466.7

*Water molecules are not included.