4DX6
Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Acriflavine resistance protein B | polymer | 1057 | 114793.3 | 3 | UniProt (P31224) Pfam (PF00873) | Escherichia coli | |
| 2 | D, E (D, E) | DARPIN | polymer | 169 | 18317.6 | 2 | SYNTHETIC CONSTRUCT (ARTIFICIAL GENE) | ||
| 3 | F, G, H, I, J... (A, B, C) | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 7 | Chemie (LMT) |
Sequence modifications
A, B, C: 1 - 1049 (UniProt: P31224)
| PDB | External Database | Details |
|---|---|---|
| Asn 616 | Gly 616 | conflict |
| Leu 1050 | - | expression tag |
| Glu 1051 | - | expression tag |
| His 1052 | - | expression tag |
| His 1053 | - | expression tag |
| His 1054 | - | expression tag |
| His 1055 | - | expression tag |
| His 1056 | - | expression tag |
| His 1057 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 381015.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 3574.3 | |
| All* | Total formula weight | 384589.4 |
