4DTK
Novel and selective pan-PIM kinase inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine/threonine-protein kinase pim-1 | polymer | 276 | 31905.2 | 1 | UniProt (P11309) Pfam (PF00069) In PDB | Homo sapiens (human) | |
| 2 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 3 | A | (5Z)-5-{2-[(3R)-3-aminopiperidin-1-yl]-3-(propan-2-yloxy)benzylidene}-1,3-thiazolidine-2,4-dione | non-polymer | 361.5 | 1 | Chemie (7LI) | |||
| 4 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 202 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31905.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 988.1 | |
| All* | Total formula weight | 32893.3 |
