4DRA

Crystal structure of MHF complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Centromere protein S	polymer	113	13328.0	4	UniProt (Q8N2Z9) Pfam (PF15630)	Homo sapiens (human)	CENP-S, Apoptosis-inducing TAF9-like domain-containing protein 1, FANCM-interacting histone fold protein 1, Fanconi anemia-associated polypeptide of 16 kDa
2	E, F, G, H (E, F, G, H)	Centromere protein X	polymer	84	9254.7	4	UniProt (A8MT69) Pfam (PF09415)	Homo sapiens (human)	CENP-X, FANCM-interacting histone fold protein 2, Fanconi anemia-associated polypeptide of 10 kDa, Retinoic acid-inducible gene D9 protein homolog, Stimulated by retinoic acid gene 13 protein homolog
3	I, J, K, L, M... (A, B, C, D, E...)	water	water		18.0	116	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 107 (UniProt: Q8N2Z9)

PDB	External Database	Details
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

E, F, G, H: 1 - 81 (UniProt: A8MT69)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	90330.7
All*	Total formula weight	90330.7

*Water molecules are not included.