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4DQE

Crystal Structure of (G16C/L38C) HIV-1 Protease in Complex with DRV

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Aspartyl proteasepolymer9910803.82Pfam (PF00077)
UniProt (by SIFTS) (P12499)
Human immunodeficiency virus 1 (HIV-1)
2C
(B)
(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATEnon-polymer547.71Chemie (017)
3D
(B)
ACETATE IONnon-polymer59.01Chemie (ACT)
4E, F
(A, B)
waterwater18.0133Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight21607.6
Non-Polymers*Number of molecules2
Total formula weight606.7
All*Total formula weight22214.3
*Water molecules are not included.

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PDB entries from 2025-12-17

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