4DQB
Crystal Structure of wild-type HIV-1 Protease in Complex with DRV
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Aspartyl protease | polymer | 99 | 10767.7 | 2 | UniProt (by SIFTS) (P12499) | Human immunodeficiency virus 1 (HIV-1) | |
| 2 | C, F (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 3 | D (B) | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE | non-polymer | 547.7 | 1 | Chemie (017) PubChem (44400512) PubChem (44578485) PubChem (23545473) PubChem (52949690) PubChem (213039) PubChem (58330571) PubChem (60170302) PubChem (70329566) PubChem (66725685) PubChem (89334570) PubChem (3001874) PubChem (89394603) PubChem (102206609) PubChem (6320435) PubChem (125136514) PubChem (6320436) PubChem (6320437) PubChem (101897907) PubChem (102206607) PubChem (102206608) PubChem (118243427) PubChem (118243428) PubChem (118243429) PubChem (125136515) PubChem (129010372) PubChem (131632443) PubChem (131667685) PubChem (134694394) PubChem (137704505) PubChem (137704865) PubChem (138631483) PubChem (138631484) PubChem (138631622) PubChem (144227995) PubChem (145507139) PubChem (147231834) PubChem (156183881) PubChem (156183911) PubChem (171370671) | |||
| 4 | E (B) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) PubChem (1061) | |||
| 5 | G (B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) PubChem (679) | |||
| 6 | H, I (A, B) | water | water | 18.0 | 209 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21535.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 844.9 | |
| All* | Total formula weight | 22380.3 |
