4DPW
Crystal structure of Staphylococcus epidermidis D283A mevalonate diphosphate decarboxylase complexed with mevalonate diphosphate and ATPgS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Mevalonate diphosphate decarboxylase | polymer | 332 | 36826.4 | 8 | UniProt (Q9FD73) Pfam (PF22700) Pfam (PF18376) | Staphylococcus epidermidis | |
| 2 | AA, I, L, N, P... (H, A, B, C, D...) | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | non-polymer | 523.2 | 8 | Chemie (AGS) | |||
| 3 | BA, J, M, O, Q... (H, A, B, C, D...) | (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID | non-polymer | 308.1 | 8 | Chemie (DP6) | |||
| 4 | CA, K, R, V (H, A, D, E) | FORMIC ACID | non-polymer | 46.0 | 4 | Chemie (FMT) | |||
| 5 | U (E) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | DA, EA, FA, GA, HA... (A, B, C, D, E...) | water | water | 18.0 | 248 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 327 (UniProt: Q9FD73)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Thr -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ala 283 | Asp 283 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 294611.1 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 6927.1 | |
| All* | Total formula weight | 301538.2 |
