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4DO9

Ternary complex of dna polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monofluoromethylene triphosphate: stereoselective binding of r-isomer

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase betapolymer33538241.71UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (human)
2B
(T)
C C G A C C G C G C A T C A G Cpolymer164829.11
3C
(P)
G C T G A T G C G (DOC)polymer103045.01
4D
(D)
G T C G Gpolymer51536.01
5E
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
6F, G, H
(A)
SODIUM IONnon-polymer23.03Chemie (NA)
7I, J, K, L, M
(A)
CHLORIDE IONnon-polymer35.55Chemie (CL)
8N
(A)
2'-DEOXY-5'-O-[(R)-{[(R)-[(R)-FLUORO(PHOSPHONO)METHYL](HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]GUANOSINEnon-polymer523.21Chemie (GFH)
9O, P, Q, R
(A, T, P, D)
waterwater18.0329Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight47651.8
Non-Polymers*Number of molecules10
Total formula weight793.7
All*Total formula weight48445.6
*Water molecules are not included.

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PDB entries from 2024-11-06

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