4DO3
Structure of FAAH with a non-steroidal anti-inflammatory drug
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Fatty-acid amide hydrolase 1 | polymer | 571 | 62872.4 | 2 | UniProt (P97612) Pfam (PF01425) In PDB | Rattus norvegicus (rat) | Anandamide amidohydrolase 1, Oleamide hydrolase 1 |
2 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
3 | A, B | CYCLOHEXANE AMINOCARBOXYLIC ACID | non-polymer | 143.2 | 2 | Chemie (OHO) | |||
4 | A, B | (2S)-2-(6-chloro-9H-carbazol-2-yl)propanoic acid | non-polymer | 273.7 | 2 | Chemie (0LA) | |||
5 | water | water | 18.0 | 533 | Chemie (HOH) |
Sequence modifications
A, B: 32 - 575 (UniProt: P97612)
PDB | External Database | Details |
---|---|---|
Met 11 | - | expression tag |
Gly 12 | - | expression tag |
Ser 13 | - | expression tag |
Ser 14 | - | expression tag |
His 15 | - | expression tag |
His 16 | - | expression tag |
His 17 | - | expression tag |
His 18 | - | expression tag |
His 19 | - | expression tag |
His 20 | - | expression tag |
Ser 21 | - | expression tag |
Ser 22 | - | expression tag |
Gly 23 | - | expression tag |
Leu 24 | - | expression tag |
Val 25 | - | expression tag |
Pro 26 | - | expression tag |
Arg 27 | - | expression tag |
Gly 28 | - | expression tag |
Ser 29 | - | expression tag |
His 30 | - | expression tag |
Met 31 | - | expression tag |
His 576 | - | expression tag |
His 577 | - | expression tag |
His 578 | - | expression tag |
His 579 | - | expression tag |
His 580 | - | expression tag |
His 581 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 125744.8 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 869.2 | |
All* | Total formula weight | 126614.0 |