4DM3
Crystal structure of human PNMT in complex adohcy, resorcinol and imidazole
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Phenylethanolamine N-methyltransferase | polymer | 289 | 31846.0 | 2 | UniProt (P11086) Pfam (PF01234) | Homo sapiens (human) | PNMTase, Noradrenaline N-methyltransferase |
| 2 | C, F (A, B) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 3 | D, G (A, B) | RESORCINOL | non-polymer | 110.1 | 2 | Chemie (RCO) | |||
| 4 | E, H (A, B) | IMIDAZOLE | non-polymer | 69.1 | 2 | Chemie (IMD) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 201 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 282 (UniProt: P11086)
| PDB | External Database | Details |
|---|---|---|
| Glu 283 | - | EXPRESSION TAG |
| His 284 | - | EXPRESSION TAG |
| His 285 | - | EXPRESSION TAG |
| His 286 | - | EXPRESSION TAG |
| His 287 | - | EXPRESSION TAG |
| His 288 | - | EXPRESSION TAG |
| His 289 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63691.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1127.2 | |
| All* | Total formula weight | 64819.1 |
