4DLO

Crystal structure of the GAIN and HormR domains of brain angiogenesis inhibitor 3 (BAI3)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Brain-specific angiogenesis inhibitor 3	polymer	382	43255.2	2	UniProt (O60242) Pfam (PF02793) Pfam (PF16489) Pfam (PF01825)	Homo sapiens (human)
2	C, E (C, E)	beta-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	2	In PDB GlyTouCan (G46874CY)
3	D (D)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	F, G, H, I, J... (A, B)	GLYCEROL	non-polymer		92.1	9	Chemie (GOL)
5	K (B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
6	P, Q (A, B)	water	water		18.0	166	Chemie (HOH)

Sequence modifications

A, B: 498 - 868 (UniProt: O60242)

PDB	External Database	Details
Ala 495	-	expression tag
Asp 496	-	expression tag
Pro 497	-	expression tag
Ser 503	Asn 503	conflict
His 869	-	expression tag
His 870	-	expression tag
His 871	-	expression tag
His 872	-	expression tag
His 873	-	expression tag
His 874	-	expression tag
His 875	-	expression tag
His 876	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	86510.5
Branched	Number of molecules	3
	Total formula weight	1565.5
Non-Polymers*	Number of molecules	10
	Total formula weight	1050.1
All*	Total formula weight	89126.0

*Water molecules are not included.